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副教授

向浩

作者:   发布时间:2014-09-03  浏览次数:


姓 名:向浩

职 称:副教授、硕导、珞珈青年学者

职 务:系主任

系 别:全球健康学系

招生专业: 流行病与卫生统计学硕士,公共卫生硕士(MPH)

Email: xianghao@whu.edu.cn

团队主页:

www.epi-air-pollution.com



一、个人简介

向浩,博士,硕士生导师,伟德betvictor-伟德betvictor官网-伟德betvictor中文官网客服副教授,全球健康学系主任,武汉大学珞珈青年学者。2009年博士毕业于华中科技大学同济医学院公共卫生学院。主要研究方向为环境流行病学、肿瘤分子流行病学和全球健康学,近年来主持和参与多项国家自然科学基金和多项省部级课题,在SCI收录杂志发表论文30余篇。参与中国首个全球健康学本科专业的申报、课程体系建设和培养方案制定等,起草首个全球健康学本科人才培养标准,2014年和2016年两次获武汉大学教学成果一等奖。主要学术兼职:中国全球健康大学联盟(CCUGH)第三届理事会副主席,中华预防医学会全球卫生分会委员,湖北省预防医学会理事,湖北省预防医学会流行病学专业委员会委员。担任国内首本全球健康领域全英文杂志“Global Health Research and Policy”编辑,Environmental International, Atmosphere Environment, Cancer,BMC Cancer和European Journal of Cancer Prevention等20余本SCI期刊的审稿人。

二、教育背景

2004/07–2009/06,华中科技大学,公共卫生学院流行病与卫生统计学系,博士

1999/09–2004/06,华中科技大学,公共卫生学院,学士

三、工作经历

2013/11至今,伟德betvictor-伟德betvictor官网-伟德betvictor中文官网客服,副教授

2011/08–2012/09,美国匹兹堡大学,公共卫生学院流行病学系,访问学者

2009/07–2013/11,武汉大学公共卫生学院流行病与卫生统计学系,讲师

四、主要研究方向

1. 环境流行病学:重点关注空气污染物(PM2.5、PM10、CO、O3、NO2和SO2等)与各种心血管疾病和呼吸系统疾病急性发作和死亡的短期效应和长期影响。

2. 肿瘤分子流行病学:研究遗传变异及环境暴露因素与肿瘤易感性的关系,重点探讨GH-IGF基因家族、MiRNA结合位点的基因多态性与结直肠癌发病的易感性,并深入探讨其发病机制。

3. 教学研究:探讨公共卫生与预防医学本科专业人才培养改革,全球健康学本科人才培养体系建设。

五、主要课题

主持:

1. 美国盖茨基金会项目“在中国实现健康相关可持续发展目标:开发循证政策行动建议(Achieving Health SDGs in China: Developing Evidence-based Policy Options for Action) ”(OPP1148464), 起止时间:2016.10-2018.10;

2. 湖北省自然科学基金“CircRNA-MYLK结合miR-19调控PTEN基因在结直肠癌中作用及机制研究”(No.2018CFB634),起止时间:2018.01-2019.12

3. 中央高校基本科研项目(自主科研学科交叉类)“基于遥感的细颗粒物暴露对心血管疾病急性效应的影响研究”(2042016kf0165), 起止时间:2016.1-2017.12

4. 湖北省卫生计生委青年人才项目“NER基因MiRNA结合位点多态性与结直肠癌易感性的关联研究”(WJ2015Q023),起止时间:2015.3-2017.3;

5. 国家自然科学基金青年基金项目“BER通路基因miRNA结合位点基因多态性与结直肠癌易感性的关联及功能研究”(81402743),起止时间:2015.1-2017.12;

6. 武汉大学自主创新项目“MiRNA 结合位点基因多态性与高血压易感性的流行病学研究”(4101039), 起止时间:2011.9-2013.9;

7. 武汉大学公共卫生学院青年基金项目 “生物钟基因多态性与大肠癌关系的分子流行病学研究”(GW1345323), 起止时间:2010.11-2013.11

8. 美国中华医学基金会(CMB)教学研究项目“基于胜任力的全球健康人才培养实践和理论探索”(13-134),起止时间:2013.01-2017.12

9.湖北省高等学校省级教学改革研究项目“基于德尔菲法的全球健康学专业课程体系评价指标的构建”,起止时间:2015.1-2016.12

10. 武汉大学医学部教学研究项目“预防医学专业本科生创新能力培养模式的理论探索”,起止时间:2013.10-2015.10

参与:

1. 国家自然基金课题“Wnt信号通路及其关键靶基因与结直肠癌遗传易感性的关联研究”(81172752),起止时间:01/01/2012-12/31/2015;

2. 国家自然基金课题“脂联素家族基因多态性与大肠癌易感性的分子流行病学

研究”(30972534),起止时间:01/01/2010-12/31/2012;

3. 国家自然基金课题“大肠癌饮食及相关因素暴露与GH 家族多态性的分子流

行病学研究”(30571598),起止时间:01/01/2006-12/31/2008;

4. 国家自然基金课题 “ 饮食因素与大肠癌相关基因交互作用的研究”(30371239),起止时间:01/01/2004-12/31/2005。

5. 武汉大学课程体系改革试点基地项目“全球健康学专业课程体系建设”,起止时间:2013.7-2016.7

五、代表性论文:

1. Pan Gao, Hao Xiang*, Suyang Liu, Yisi Liu, Shengjie Dong, Feifei Liu, Wenyuan Yu, Xiangyu Li, Li Guan, Yuanyuan Chu, Zongfu Mao, Shu Chen and Shenglan Tang.Evaluation of a consulting training course for international development assistance for health. BMC Medical Education, 2018,18:234

2. Li X, Liu Y, Liu F, Wang Y, Yang X, Yu J, Xue X, Jiao A, Lu Y, Tian L, Deng S, Xiang H*.Analysis of short-term and sub-chronic effects of ambient air pollution on preterm birth in central China.Environmental Science and Pollution Research, 2018 May 2. doi: 10.1007/s11356-018-2061-8.

3. Liu, F, Zhang F, Li X, Liu Q, Liu W, Song P, Qiu Z, Dong Y, Xiang H*. Prognostic role of miR-17-92 family in human cancers: evaluation of multiple prognostic outcomes.Oncotarget. 2017 Jul 8;8(40):69125-69138. doi: 10.18632/oncotarget.19096.

4. Li X, Huang S, Jiao A, Yang X, Yun J, Wang Y, Xue X, Chu Y, Liu F, Liu Y, Ren M, Chen X, Li N, Lu Y, Mao Z, Tian L, Xiang H*. Association between ambient fine particulate matter and preterm birth or term low birth weight: An updated systematic review and meta-analysis. Environmental Pollution. 2017 Apr 27. pii: S0269-7491(16)32550-7. doi: 10.1016

5. Meng Ren, Na Li, Zhan Wang, Yisi Liu, Xi Chen, Yuanyuan Chu, Xiangyu Li, Zhongmin Zhu, Liqiao Tian, Hao Xiang*.The Short-term Effect of Air Pollutants on Respiratory Diseases Mortality in Wuhan, China: Comparison of Time Series and Case-crossover Analysis.Scientific Report2017, 7:40482

6. Feifei Liu, Lijing Yan, Zhan Wang, Yuanan Lu, Yuanyuan Chu, Xiangyu Li, Yisi Liu, Dongsheng Rui, ShaofaNie, Hao Xiang*. Metformin therapy and risk of colorectal adenomas and colorectal cancer in type 2 diabetes mellitus patients: A systematic review and meta-analysis.Oncotarget Dec 1. doi: 10.18632/oncotarget.13762.

7. Feifei Liu, Keith Dear, Lei Huang, Li Liu, Yun Shi, ShaofaNie,Yisi Liu, Yuanan Lu, HaoXiang*. Association between microRNA-27a rs895819polymorphism and risk of colorectal cancer:A meta-analysis. Cancer Genetics2016(209):388–394

8. Yuanyuan Chu, Yisi Liu, Yuanan Lu, Lichen Yu, Hanson Lu, Yulin Guo, Fengfeng Liu, Yanyan Wu, Zongfu Mao, Meng Ren, Na Li, Xi Chen, HaoXiang*.Propensity to Migrate and Willingness to Pay Related to Air Pollution among Different Populations in Wuhan, China. Aerosol and Air Quality Research.2017, 17:752-760,doi: 10.4209/aaqr.2016.05.0178

9. Yisi Liu, Yuanyuan Chu, Meng Ren, Xi Chen, Na Li,Xiangyu Li,Feifei Liu,Liqiao Tian, Zhongmin Zhu, Yuanan Lu, Zongfu Mao, Hao Xiang*. Using Satellite Remote Sensing Data to Estimate Health Effects of Particulate Matters: a Novel Application of Aerosol Optical Depth in epidemiological Studies.Science of Total Environment (under review)

10. YisiLiu, Xi Chen, Keith Dear, Zhan Wang, ShuqiongHuang, YuananLu, Na Li, Meng Ren, Yuanyuan Chu, Xiangyu Li, FeifeiLiu, LiqiaoTian, ZhongminZhu, Hao Xiang*. Non-accidental and Cardiovascular Diseases Mortality Associated with Long-term Exposure of PM2.5 Derived from Satellite Aerosol Optical Depth: A Systematic Review and Meta-Analysis. Scientific Report(under review)

11. Guo Y, Liu F, Lu Y, Mao Z, Lu H, Wu Y, Chu Y, Yu L, Liu Y, Ren M, Li N, Chen X, Hao Xiang*.Factors Affecting Parent's Perception on Air Quality-From the Individual to the Community Level.Int J Environ Res Public Health. 2016, 13(5).

12. Yuanyuan Chu, Yisi Liu, Xiangyu Li, Zhiyong Liu, Hanson Lu, Yuanan Lu,Zongfu Mao, Xi Chen, Na Li, Meng Ren, Feifei Liu, Liqiao Tian,Zhongmin Zhu, Hao Xiang*. A Review on Predicting Ground PM2.5 ConcentrationUsing Satellite Aerosol Optical Depth.Atmosphere 2016, 7, 129.

13. Tianhao Zhang, Zhongmin Zhu, Wei Gong, Hao Xiang, Ying Li and Zhenzhen Cui.Characteristics of Ultrafine Particles andTheir Relationships with Meteorological Factorsand Trace Gases in Wuhan, Central China. Atmosphere 2016, 7, 96.

14. Tianhao Zhang, Zhongmin Zhu, Wei Gong, Hao Xiang and Ruimin Fang.Characteristics of Fine Particles in an UrbanAtmosphere-Relationships with MeteorologicalParameters and Trace GasesInt. J. Environ. Res. Public Health 2016, 13, 807.

15. Yisi Liu, Xi Chen, Shuqiong Huang, Liqiao Tian, Yuan’an Lu, Yan Mei,Meng Ren, Na Li, Li Liu and Hao Xiang*. Association between Air Pollutants and Cardiovascular DiseaseMortality in Wuhan, China.Int J Environ Res Public Health. 2015, 12, 3506-3516.

16. Xiang H, Mertz KJ, Arena VC, Brink LL, Xu X, Bi Y, Talbott EO. Estimation of short-term effects of air pollution on stroke hospital admissions in Wuhan, China. PLoS One. 2013, 12, 8(4):e61168.

17. Hao Xiang*, Ying Wang, ShaofaNie. Meta-analysis of the association between insulin-like growth factor binding protein 3 genetic polymorphisms and colorectal cancer susceptibility, PLOS ONE, 2013, 8(3):e59665.

18. Ying Xia, Jiafa Liu, Tingming Shi, Hao Xiang*, Yongyi, Bi*. Prevalence of Pneumoconiosis in Hubei, China from 2008 to 2013. Int J Environ Res Public Health.2014, 11(9): 8612-8621.

19. Hao Xiang, Li Liu, Guang-di Chu, Sheng Wei, Jian-ping Liu, Yi-hua Xu, Ji-gui Chen, Chong-jian Wang, Qing-Yi Wei, Shao-fa Nie*. Association between two functional polymorphisms of insulin-like growth factor binding protein 3 and colorectal cancer risk in a Chinese population. Journal of Toxicology and Environmental Health, Part A.2009, 72(11-12): 706-711.

20. Zhang F, Xiang H(Co-first Author), Fan Y, Ganchuluun TA, Kong W, Ouyang Q, Sun J, Cao B, Jiang H, Nie S*. The effects of sulfonylureas plus metformin on lipids, blood pressure, and adverse events in type 2 diabetes: a meta-analysis of randomized controlled trials. Endocrine.2013, 44(3):648-58.

21. Zhong R, Liu L, Zou L, Sheng W, Zhu B, Xiang H, Chen W, Chen J, Rui R, Zheng X, Yin J, Duan S, Yang B, Sun J, Lou J, Liu L, Xie D, Xu Y, Nie S*, Miao X. Genetic variations in the TGFβ signaling pathway, smoking and risk of colorectal cancer in a Chinese population. Carcinogenesis.2013, 34(4):936-42.

22. Liu L, Zhong R, Wei S, Xiang H, Chen J, Xie D, Yin J, Zou L, Sun J, Chen W, Miao X, NieS.The Leptin Gene Family and Colorectal Cancer: Interaction with Smoking Behavior and Family History of Cancer. PLOS ONE. 2013, 8(4):e60777.

23. Liu L, Zhong R, Wei S, Yin JY, Xiang H, Zou L, Chen W, Chen JG, Zheng XW, Huang    LJ, Zhu BB, Chen Q, Duan SY, Rui R, Yang BF, Sun JW, Xie DS, Xu YH, Miao XP, N    ie SF*. Interactions between genetic variants inthe adiponectin, adiponectin receptor 1and e    nvironmental factors on the risk of colorectal cancer.  PLOS ONE. 2011, 6(11):e27301.