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副教授

梁晓晖

作者:   发布时间:2014-09-15  浏览次数:

姓名:梁晓晖                                                          

职务、职称:副教授,硕导

系别:全球健康学系

联系电话:18971639101

邮箱:xhliang@whu.edu.cn

个人简介:

    湖南医科大学医疗系学士,新加坡国立大学博士,美国约翰霍普金斯医学院肿瘤科博士后。曾在中南大学湘雅医院感染科,清华大学医院内科和武汉大学人民医院任临床医生,2012年进入公共卫生学院。科研方面曾以第一作者发表SCI论文5篇,通讯作者2篇,参与作者发表SCI文章4篇。教学方面,参与的教学课程包括:卫生学,劳动卫生学,卫生法律法规与监督学,医学文献检索,环境污染与人类健康,全球健康概论和专业英文。

 

主要研究课题:

1,全球健康信息平台构建

2. 儿童铅中毒的临床调查

3. 食品药品安全

4. 环境与肿瘤

 

代表性论著

 

1.    Liang XiaoHui, Heng Chew Kiat, Cheung Wai, Wang De Yun.  Absent of the toll-like receptor 4 gene polymorphisms Asp200G1y and Thr399I1e in Singaporean Chinese.  Therapeutics and clinical risk management, 2005: 1(3): 243-46。

2. Liang XiaoHui, Cheung Wai, Heng Chew Kiat, Wang De Yun.  Reduced transcriptional activity in individuals with interleukin-18 gene variants detected from functional but not association study.  Biochemical and Biophysical Research Communication, 2005: 338: 736-41

3.    Liang XiaoHui, Heng Chew Kiat, Cheung Wai, Liu Jian Jun, Li Chun Wei, Lim Bing, Wang De Yun.  CD14 promoter polymorphisms have no functional significance and are not associated with atopic phenotypes.  Pharmacogenetics and Genomics, 2006: 16: 229-36

4. Liang XH, Lau QC, Salto-Tellez M, Putti TC, Loh M, Sukumar S. Mutational hotspot in exon 20 of PIK3CA in breast cancer among Singapore Chinese. Cancer Biol Ther. 2006: 5 (5): 544-8

5.  Chen H, Zhang H, Lee J, Liang X, Wu X, Zhu T, Lo PK, Zhang X, Sukumar S. HOXA5 acts directly downstream of retinoic acid receptor beta and contributes to retinoic acid-induced apoptosis and growth inhibition. Cancer Res. 2007 Sep 1;67(17):8007-13.

6. Liang XiaoHui, Cheung Wai, Wang De Yun. Differential and opposed transcriptional effects of IL-18 gene polymorphisms (-137, +113 and +127) in human HepG2, Hela, U937 and THP-1 cells. Med Sci Monit, 2008; 14(1): BR8-13.

7. Chen H, Lee JS, Liang X, Zhang H, Zhu T, Zhang Z, Taylor ME, Zahnow C, Feigenbaum L, Rein A, Sukumar S. Hoxb7 inhibits transgenic HER-2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis. Cancer Res. 2008 May 15;68(10):3637-44. Epub 2008 May 7。

8. Lo PK, Watanabe H, Cheng PC, Teo WW, Liang X, Argani P, Lee JS, Sukumar S. J Mol Diagn. MethySYBR, a novel quantitative PCR assay for the dual analysis of DNA methylation and CpG methylation density. 2009 Sep;11(5):400-14.

9.  Lo PK, Lee JS, Liang X, Han L, Mori T, Fackler MJ, Sadik H, Argani P, Pandita TK, Sukumar S. Epigenetic inactivation of the potential tumor suppressor gene FOXF1 in breast cancer.Cancer Res. 2010 Jul 15;70(14):6047-58. Epub 2010 Jun 29.

10.Li Y, Wu S, Xiang Y, Liang X.An investigation of outpatient children's blood lead level in Wuhan China. PLoS One. 2014 Apr 16; 9(4): e95284.(Corresponding author)

11. Shao J, Li Y, Zhao P, Yue X, Jiang J, Liang X, He X. Association of mTOR polymorphisms with cancer risk and clinical outcomes: a meta-analysis. LoS One. 2014 May 9;9(5):e97085.(Co-Corresponding author)。